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Pharmaceuticals

I INTRODUCTION 

Pharmaceuticals, medicinal drugs used for the prevention and control of disease. The civilizations of ancient India, China and the Mediterranean and Middle East discovered and employed numerous medicinal plants and minerals-including some, such as ipecac, that remain in use today. The study of drugs emerged as the distinct profession of pharmacy in 8th century Baghdad, and the first pharmacies appeared around 1180 in Montpellier, France. The profession's beginnings in the U.S. date from the American Revolution, but the United States mainly remained dependent on European drug sources until World War I, when the cutoff of the European supply stimulated American production. In the 20th century, the thousands of new drugs placed in the hands of physicians through research and development have wrought a virtual revolution in medical practice.
Drugs are divided into two groups: the ethical, or prescription, drugs, normally available only through prescription; and the proprietary, or patent, drugs, sold over the counter for relief of minor and temporary ailments. A rapidly growing field is veterinary pharmaceuticals.


II RESEARCH AND TESTING 

In the wake of the development of the sulfa drugs in the 1930s and penicillin in the '40s, the pharmaceutical industry became geared to intensive research on antibiotics, antihistamines, steroid hormones, vitamins, and many other kinds of drugs. Discovery of a new drug triggers an elaborate testing program, first on small animals such as mice, then on larger animals such as monkeys and dogs. In the U.S., approval must be obtained from the Food and Drug Administration for tests on humans, first on healthy volunteers, then on patients suffering from the affliction the drug is intended to combat.
Successive legislation has banned adulterated and misbranded products, prescribed testing by manufacturers, and required manufacturers to prove the efficacy of their products. Narcotics are under special government control via the Bureau of Narcotics and Dangerous Drugs (see Drug Enforcement Administration).


III DEVELOPMENT AND PRODUCTION 

Once a new drug is approved for marketing, it must be combined with ingredients (excipients) to convert it to liquid or capsule form. Usually, production in a pilot plant is necessary to identify manufacturing problems before mass production begins.
The introduction of so-called generic drugs to the U.S. industry in the 1970s involved a controversy over the differences in wholesale price between brand-name proprietary drugs and the same drugs sold under their scientific (generic) names. Critics charged that the price differences were not justified and that many pharmacists failed to pass along much of the cost benefits in selling the generic products.

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© 1998-2009 by Compare Generics

Norman@thehormoneshop.com
This page was last updated on 01/30/10

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These statements have not been evaluated by the Food & Drug
Administration. These products are not intended to diagnose, cure, treat or prevent
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Notice: This information  is provided for educational and nutritional purposes only. Any medical procedures, dietary changes or the use of dietary supplements discussed herein should only be undertaken on the advice of a qualified medical doctor. Although some are listed and sold as dietary supplements they are not innocuous, inert substances; rather they can and do affect vital systems within the human body and it is for this reason that you are urged to find a medical doctor who will work with you in monitoring and maintaining your well being.

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